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Blogs
Integrating In Silico Tools with Organ-on-a-Chip to advance ADME studies
Knowing a drug’s bioavailability during lead optimization is crucial as it directly influences dosing strategy, therapeutic efficacy, safety margins, and formulation design.
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Brochures & Flyers
PhysioMimix Bioavailability assay kit: Human 18 brochure
Modernize your workflow with the only in vitro bioavailability assessment tool on the market. Elevate your workflow with our all-in-one Bioavailability assay kit containing everything you need to recreate our human in vitro Gut/Liver-on-a-chip model and Bioavailability assay in your laboratory.
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Videos and animations
PhysioMimix® bioavailability assay kit: Human 18 for simultaneous oral and intravenous in vitro bioavailability profiling
Discover the PhysioMimix® Bioavailability assay kit: Human 18, the only in vitro tool for profiling human bioavailability. This Organ-on-a-chip solution bridges the gap between in vitro and in vivo studies, enhancing preclinical ADME testing for CROs, pharma, and biotech. Explore how it streamlines lead optimization and improves drug development accuracy.
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Scientific publications
Normalization of organ-on-a-Chip samples for mass spectrometry based proteomics and metabolomics via Dansylation-based assay
Scientific publications
Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro
Scientific publications
Multiorgan microphysiological systems as tools to interrogate interorgan crosstalk and complex diseases
Scientific publications
Characterizing the reproducibility in using a liver microphysiological system for assaying drug toxicity, metabolism and accumulation
Scientific publications
Interconnected microphysiological systems for quantitative biology and phamarcology studies
Scientific publications
Perfused human hepatocyte microtissues identify reactive metabolite-forming and mitochondria-perturbing hepatotoxins
Scientific publications
Integrated assessment of diclofenac biotransformation, pharmacokinetics and omics-based toxicity in a 3D human liver-immunocompetent co-culture system
Scientific publications