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Blogs
Integrating In Silico Tools with Organ-on-a-Chip to advance ADME studies
Knowing a drug’s bioavailability during lead optimization is crucial as it directly influences dosing strategy, therapeutic efficacy, safety margins, and formulation design.
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Brochures & Flyers
PhysioMimix Bioavailability assay kit: Human 18 brochure
Modernize your workflow with the only in vitro bioavailability assessment tool on the market. Elevate your workflow with our all-in-one Bioavailability assay kit containing everything you need to recreate our human in vitro Gut/Liver-on-a-chip model and Bioavailability assay in your laboratory.
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Videos and animations
PhysioMimix® bioavailability assay kit: Human 18 for simultaneous oral and intravenous in vitro bioavailability profiling
Discover the PhysioMimix® Bioavailability assay kit: Human 18, the only in vitro tool for profiling human bioavailability. This Organ-on-a-chip solution bridges the gap between in vitro and in vivo studies, enhancing preclinical ADME testing for CROs, pharma, and biotech. Explore how it streamlines lead optimization and improves drug development accuracy.
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Application notes
Accelerating DILI Prediction: A High-Throughput Liver-on-a-Chip Solution
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A liver microphysiological system to study the delivery and efficacy of oligonucleotide-based therapeutics
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Evaluating a human DILI assay kit’s ability to unlock complex mechanisms of toxicity
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Developing a translational biomarker panel for use in pre-clinical advanced in vitro studies of Non-alcoholic steatohepatitis
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Connecting the gut and liver
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Alveolar and Bronchial Microphysiological Systems for respiratory infection research and therapeutics evaluation
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Human liver microphysiological system for predicting the drug-induced liver toxicity of differing drug modalities
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Microphysiological system for studying fatty liver disease and its impact on drug-induced liver injury
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Improved prediction of oral bioavailability using a gut-liver microphysiological system
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Drug metabolism in a gut-liver microphysiological system
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